This is a variance kernel. I used these in developing imaging alignment.   Cone Focused AO imaging

Managing the imaging

 Our original controls were developed by Remy Tumbar and Dan Sumorok (who was getting an MS at BU).  They were a very versatile system at the time, incorporating multiple approaches to centroiding and incorporating Tikhinov regularization.  Weiyao Zou added specialized capabilities for our two mirror woofer tweeter system with damping.  Weiyao and later Alberto de Castro improved the ability to work with difficult eyes.   Gang Huang added Lucky Averaging to optimize  contrast.  Lucie Sawides added direct mapping of steerable imaging  onto the Heidelberg Spectralis (tm).   

Relevant Papers

  • Webb, RH, Albanese, MJ, Zhou, Y, Bifano, T and Burns, SA “A stroke amplifier for deformable mirrors” Applied Optics 43(28), 5330-5333 , 2004, PMID: 15495423
  • Burns, S.A., Tumbar, R., Elsner, A.E., Ferguson, D., & Hammer, D.X.. Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope. Journal of the Optical Society of Americaa-Optics Image Science and Vision, 24 (5), 1313-1326., 2007, PMCID: PMC2443858
  • Zou, W, Qi, X, Burns, SA, “Wavefront aberration sorting and correction for dual-deformable-mirror adaptive optics system” Optics Letters, Vol. 33, Issue 22, pp. 2602-2604, 2008 PMCID: PMC2738988  
  • Zou, W, Burns, SA, "High-accuracy wavefront control for retinal imaging with Adaptive-Influence-Matrix Adaptive Optics" Optics Express. Vol. 17 Issue 22, pp.20167-20177 (2009), PMCID: PMC2882182   
  • Zou, W, Qi, X, Burns, SA, “Woofer-tweeter adaptive optics scanning laser ophthalmoscopic imaging based on Lagrange-multiplier damped least-squares algorithm”, Biomedical Optics Express, Vol. 2, Issue 7, pp. 1986-2004       doi:10.1364/BOE.2.001986. (2011) PMID: 21750774 PMCID: PMC3130583  
  • Huang, G, Zhong, Z, Zou W, Burns, SA “Lucky Averaging: Quality improvement on Adaptive Optics Scanning Laser Ophthalmoscope Images” Optics Letters, Vol. 36, No. 19 3786-3789 (2011). PMCID: PMC3407537
  • Zou, W, Qi, X, Huang, G, Burns, SA,  Improving wavefront boundary condition for in vivohigh resolution adaptive optics ophthalmic imaging, Biomedical Optics Express. Vol. 2, Issue 12, pp. 3309-3320 (2011) PMID: 22162821 PMCID: PMC3233250  
  • Zou W, Burns SA.  Testing of Lagrange multiplier damped least-squares control algorithm for woofer-tweeter adaptive optics. Appl Opt. 2012 Mar 20;51(9):1198-208. doi: 10.1364/AO.51.001198. PMID: 2441462. PMCID: PMC3407539
  • Chui, T. Y. P., D. A. VanNasdale and S. A. Burns (2012). "The use of forward scatter to improve retinal vascular imaging with an adaptive optics scanning laser ophthalmoscope." Biomed. Opt. Express 3(10): 2537-2549. PMID: 23082294 PMCID: PMC3470005 
  • de Castro Alberto, Huang Gang, Sawides, Lucie, Luo, Ting, Burns, Stephen A., Rapid high resolution imaging with a dual-channel scanning technique, Optics Letters: 2016 41(8) 1881-1884  PMID: 27082369 PMCID: PMC5535314
  • Marcos S; Werner JS; Merrigan WH; Burns, SA, Artal P; Atchison D; Hampson KM; Legras R; Lundstrom L; Yoon G; Carroll J; Choi SS; Doble N; Dubis AM; Dubra A; Elsner AE; Jonnal R; Miller DT; Paques M; Smithson HE; Young LK; Zhang Y; Campbell M; Hunter J; Metha A; Palczewska G; Schallek J; Sincich LC, Vision Science and Adaptive Optics, The State of the Field. 2017, 132: 3–33 28212982PMCID: PMC5437977
  • de Castro A, Sawides, L. Qi, X, Burns, SA, Adaptive Optics Retinal Imaging with Automatic Detection of the Pupil and its Boundary in Real time using Shack Hartmann Images, 2017, Applied Optics 2017, 56, 6748-6754  PMID: 29048013 PMCID: PMC5973534