Stephen A. Burns, Indiana University, Vision Science Lab

Stephen A. Burns, Indiana University, Vision Science Lab Stephen A. Burns, Indiana University, Vision Science Lab Stephen A. Burns, Indiana University, Vision Science Lab

Stephen A. Burns, Indiana University, Vision Science Lab

Stephen A. Burns, Indiana University, Vision Science Lab Stephen A. Burns, Indiana University, Vision Science Lab Stephen A. Burns, Indiana University, Vision Science Lab
  • Home
  • AO Systems
  • AO Control
  • Vascular Imaging
  • Cones
  • CV
  • Approaches
    • Psychopysical
    • ERG
    • Wavefronts
    • Reflectometry and Imaging
  • Vision Science Program
  • More
    • Home
    • AO Systems
    • AO Control
    • Vascular Imaging
    • Cones
    • CV
    • Approaches
      • Psychopysical
      • ERG
      • Wavefronts
      • Reflectometry and Imaging
    • Vision Science Program
  • Home
  • AO Systems
  • AO Control
  • Vascular Imaging
  • Cones
  • CV
  • Approaches
    • Psychopysical
    • ERG
    • Wavefronts
    • Reflectometry and Imaging
  • Vision Science Program

Managing the AO Imaging

Controlling AO and Relating the results to clinical imaging modalities

  Our original controls was developed by Remy Tumbar and Dan Sumorok.  The control was a versatile system for the time, incorporating multiple approaches to centroiding and incorporating regularization.  Weiyao Zou added capabilities two mirror woofer tweeter system and later Alberto de Castro improved the ability to work with difficulty eyes.

 

Improving the clinical utility of AO.

Lucie Sawides added direct mapping of steerable imaging  onto the Heidelberg Spectralis (tm).   Ting Luo as part of her thesis has added fully automated montaging of retinal images and I am working on building annotation layers into these montages to better automatically document measurements.
 

Relevant Papers

  • Webb, RH, Albanese, MJ, Zhou, Y, Bifano, T and Burns, SA “A stroke amplifier for deformable mirrors” Applied Optics 43(28), 5330-5333 , 2004, PMID: 15495423
  • Burns, S.A., Tumbar, R., Elsner, A.E., Ferguson, D., & Hammer, D.X.. Large-field-of-view, modular, stabilized, adaptive-optics-based scanning laser ophthalmoscope. Journal of the Optical Society of Americaa-Optics Image Science and Vision, 24 (5), 1313-1326., 2007, PMCID: PMC2443858
  • Zou, W, Qi, X, Burns, SA, “Wavefront aberration sorting and correction for dual-deformable-mirror adaptive optics system” Optics Letters, Vol. 33, Issue 22, pp. 2602-2604, 2008 PMCID: PMC2738988  
  • Zou, W, Burns, SA, "High-accuracy wavefront control for retinal imaging with Adaptive-Influence-Matrix Adaptive Optics" Optics Express. Vol. 17 Issue 22, pp.20167-20177 (2009), PMCID: PMC2882182   
  • Zou, W, Qi, X, Burns, SA, “Woofer-tweeter adaptive optics scanning laser ophthalmoscopic imaging based on Lagrange-multiplier damped least-squares algorithm”, Biomedical Optics Express, Vol. 2, Issue 7, pp. 1986-2004       doi:10.1364/BOE.2.001986. (2011) PMID: 21750774 PMCID: PMC3130583  
  • Huang, G, Zhong, Z, Zou W, Burns, SA “Lucky Averaging: Quality improvement on Adaptive Optics Scanning Laser Ophthalmoscope Images” Optics Letters, Vol. 36, No. 19 3786-3789 (2011). PMCID: PMC3407537
  • Zou, W, Qi, X, Huang, G, Burns, SA,  Improving wavefront boundary condition for in vivohigh resolution adaptive optics ophthalmic imaging, Biomedical Optics Express. Vol. 2, Issue 12, pp. 3309-3320 (2011) PMID: 22162821 PMCID: PMC3233250  
  • Zou W, Burns SA.  Testing of Lagrange multiplier damped least-squares control algorithm for woofer-tweeter adaptive optics. Appl Opt. 2012 Mar 20;51(9):1198-208. doi: 10.1364/AO.51.001198. PMID: 2441462. PMCID: PMC3407539
  • Chui, T. Y. P., D. A. VanNasdale and S. A. Burns (2012). "The use of forward scatter to improve retinal vascular imaging with an adaptive optics scanning laser ophthalmoscope." Biomed. Opt. Express 3(10): 2537-2549. PMID: 23082294 PMCID: PMC3470005 
  • de Castro Alberto, Huang Gang, Sawides, Lucie, Luo, Ting, Burns, Stephen A., Rapid high resolution imaging with a dual-channel scanning technique, Optics Letters: 2016 41(8) 1881-1884  PMID: 27082369 PMCID: PMC5535314
  • Marcos S; Werner JS; Merrigan WH; Burns, SA, Artal P; Atchison D; Hampson KM; Legras R; Lundstrom L; Yoon G; Carroll J; Choi SS; Doble N; Dubis AM; Dubra A; Elsner AE; Jonnal R; Miller DT; Paques M; Smithson HE; Young LK; Zhang Y; Campbell M; Hunter J; Metha A; Palczewska G; Schallek J; Sincich LC, Vision Science and Adaptive Optics, The State of the Field. 2017, 132: 3–33 https://doi.org/10.1016/j.visres.2017.01.006PMID: 28212982PMCID: PMC5437977
  • de Castro A, Sawides, L. Qi, X, Burns, SA, Adaptive Optics Retinal Imaging with Automatic Detection of the Pupil and its Boundary in Real time using Shack Hartmann Images, 2017, Applied Optics 2017, 56, 6748-6754 https://doi.org/10.1364/AO.56.006748  PMID: 29048013 PMCID: PMC5973534
  • Luo, T, Gilbert, RN, Sapoznik, KA, Walker, BR, Burns, SA. Automatic montaging of adaptive optics retinal images based on graph theory Biomedical Optics Express (2024): ol. 15, pp. 1021-1037 (2024)  https://doi.org/10.1364/BOE.505013

 


Downloads

Zou_AO_ImageQuality (pdf)Download
HuangClinicalPlanningModule_OVS2012 (pdf)Download
HuangLuckyAveraging (pdf)Download
ZouDual DM DLS AOLSO_BME (pdf)Download
ZouVarirableInfluenceMatrix (pdf)Download
Zou_DualMirrorControlOL2008 (pdf)Download
BurnsJOSAA_IndianaAOSLO_2007 (pdf)Download
deCastroAO-292377_PupilControl (pdf)Download
This is a variance kernel. I used these in developing imaging alignment.   Cone Focused AO imaging

Managing the imaging

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